董惠钧(1977.04- ),男,博士,副教授,硕士研究生导师。
教育背景
2003.09~2006.09 浙江大学生物化学与分子生物学专业,获博士学位
2000.09~2003.07 天津科技大学发酵工程专业,获硕士学位
1996.09~2000.07 天津科技大学生物化工专业,获学士学位
研究方向
(1) 药用微生物合成生物学研究
(2) 中药经方药效和制剂研究
工作经历
2013.01~至今 永利总站ylzz55
2006.09~2012.12 鲁南制药集团股份有限公司
科研项目(横向)
(1)健脾止遗颗粒剂的研制,2018-2021年,项目负责人。
(2)生物农药武夷菌素的分离纯化,2014-2017年,项目负责人。
发表论文情况(近三年)
(1)Wen Gao, Li Jin, Chunhong Liu, Ning Zhang, Ruiyan Zhang, Zuzana Bednarikova, Zuzana Gazova, Anirban Bhunia, Hans-Christian Siebert, Huijun Dong*. Inhibition behavior of Sennoside A and Sennoside C on amyloid fibrillation of human lysozyme and its possible mechanism. International Journal of Biological Macromolecules, 2021,178:424-433.
(2)Ning Zhang, Li Jin, Chunhong Liu, Ruiyan Zhang, Hans-Christian Siebert, Yanhui Li, Gabriele Loers, Athanasios K. Petridis, Zhangyong Xia, Huijun Dong, Xuexing Zheng. An antarctic krill oil-based diet elicits neuroprotective effects by inhibiting oxidative stress and rebalancing the M1/M2 microglia phenotype in a cuprizone model for demyelination. Journal of Functional Foods, 2021, 76:104309.
(3)Li Jin, Wen Gao, Chunhong Liu, Ning Zhang, Shruti Mukherjee, Ruiyan Zhang, Huijun Dong, Anirban Bhunia, Zuzana Bednarikova, Zuzana Gazova, Min Liu, Jun Han, Hans-Christian Siebert. Investigating the inhibitory effects of entacapone on amyloid fibril formation of human lysozyme[J]. International Journal of Biological Macromolecules, 2020, 161:1393-1404.
(4)Huijun Dong*, Xue Yue, Bingyu Yan, Wen Gao, Shuai Wang, Yongquan Li. Improved A40926 production from Nonomuraea gerenzanensis using the promoter engineering and the co-expression of crucial genes[J]. Journal of Biotechnology, 2020, 324:28-33.
(5)Xue Yue, Tianyu Xia, Shuai Wang, Huijun Dong*,Yongquan Li. Highly efficient genomic editing in N. gerenzanensis using an inducible CRISPR/Cas9/RecA system[J]. Biotechnology Letters, 2020, 42:1699-1706.
(6)Xue Yue, Bingyu Yan, Shuai Wang, Wen Gao, Ruiyan Zhang, Huijun Dong*. Preparation of pH-responsive alginate–chitosan microspheres for L-Valine loading and their effects on the A40926 production[J]. Current Microbiology, 2020, 77:1016-1023.
(7)孙苗苗, 李向阳, 李华利, 刘红粉, 王帅, 张瑞岩, 董惠钧. 鲜鸡肠与鸭肠、鹅肠中金属元素含量对比研究[J]. 食品安全质量检测学报, 2020, 11(6):1992-1996.
(8)岳雪, 王帅, 李大成, 王勇健, 董惠钧. 野野村放线菌ATCC 39727的双组份信号转导系统的生物信息学分析[J]. 中国抗生素杂志, 2019, 4:413-421.
(9)洪虹, 岳雪, 李大成, 王炳全, 董惠钧. 多孔木霉色素的结构鉴定和合成基因簇分析[J].生物加工过程, 2018,16(3):22-28.