贾殿隆 博士 

Email：dianlongjia@sina.com

 教育背景

2010/09-2015/06，四川大学，再生医学研究中心，硕博连读

2006/09-2010/06，曲阜师范大学，生命科学学院，本科

2015/07-至今，永利总站ylzz55，永利总站ylzz55，讲师

科研项目

1.国家自然科学基金面上项目，81273419，融合高亲和性肿瘤导向肽增强sTRAIL抗肿瘤作用及机制研究，参加

2.国家自然科学基金面上项目，81172868，T细胞活化和增殖共抑制双功能分子的构建及其在类风湿性关节炎实验治疗中的应用，参加

3.青年科学基金项目，81102366，CendR基序肿瘤导向肽iTNP的组织穿透性及其作为药物载体的研究，参加

研究方向

   重组蛋白药物、肿瘤靶向药物

发表论文

   (1) Dianlong Jia#, Hao Yang, Ze Tao, Lin Wan, Jingqiu Cheng, Xiaofeng Lu*, Preparation and characterization of a novel variant of human tumor necrosis factor-related apoptosis-inducing ligand from the rhesus monkey, Macaca mulatta, Applied Microbiology and Biotechnology, 2015, 69(5):AB337.

   (2) Dianlong Jia#, Hao Yang, Lin Wan, Jingqiu Cheng, Xiaofeng Lu*,  Production of bioactive, SUMO-modified, and native-like TNF-α of the rhesus monkey, Macaca mulatta, in Escherichia coli, Applied Microbiology and Biotechnology, 2012, 93(6):2345-2355.

   (3) Nie Q#, Jia D#, Yang H, et al. Conjugation to 10 kDa linear PEG extends serum half-life and preserves the receptor-binding ability of mmTRAIL with minimal stimulation of PEG-specific antibodies. Mol Pharm, 2016.

 (4) Tao Su#, Hao Yang, Qing Fan, Dianlong Jia, Lin Wan, Ze Tao, Lin Wan, Xiaofeng Lu*,  Enhancing the circulating half-life and the antitumor effects of a tumor-selective cytotoxic peptide by exploiting endogenous serum albumin as a drug carrier, International Journal of Pharmaceutics, 2016, 499(1-2).

(5) Ze Tao#, Yang Hao, Dianlong Jia, Lin Wan, Jingqiu Cheng, Xiaofeng Lu*, Molecular cloning, recombinant expression and characterization of GMCSF from the rhesus monkey, Macaca mulatta, Developmental and Comparative Immunology, 2013, 40(1):69–77.

(6)Li R, Yang H, Jia D, et al. Fusion to an albumin-binding domain with a high affinity for albumin extends the circulatory half-life and enhances the in vivo, antitumor effects of human TRAIL[J]. Journal of Controlled Release Official Journal of the Controlled Release Society, 2016, 228:96-106.